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PACKAGE LEAFLET: INFORMATION FOR THE USER Novgos 3.6 mg Implant Goserelin Read all of this leaflet carefully before you start using this medicine. • Keep this leaflet. You may need to read it again. • If you have any further questions, ask your doctor.

• This medicine has been prescribed for you. Do not pass it on to others. It may harm them, even if their symptoms are the same as yours. • If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor. In this leaflet: 1. What Novgos is and what it is used for 2.

Before you use Novgos 3. How to use Novgos 4. Possible side effects 5. How to store Novgos 6. Further information 1. WHAT Novgos IS AND WHAT IT IS USED FOR Novgos is a medicine that acts like a hormone.

It belongs to a group of medicines called LHRH agonists. It reduces the production of the male sexual hormone (testosterone) or the female sexual hormone (oestrogen) in the body. Novgos is used in men to treat prostate cancer. BEFORE YOU USE Novgos Do not use Novgos • if you are allergic to goserelin or any of the other ingredients of Novgos. • in children. Take special care with Novgos • if you have or have had problems passing urine or if you have or have had problems with your back. Please, tell your doctor if so.

Previous treatment • if you had a previous treatment with another medicine in this group because they can cause a small loss of calcium from the bones (thinning of bones). Some recovery of this loss can occur when treatment is stopped. If you are suffering from any disease which affects the strength of your bones please make sure that your doctor is aware of this. Children • Novgos must not be used in children. Using other medicines 1 Please tell your doctor if you are taking or have recently taken any other medicines, including medicines obtained without prescription.

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Driving and using machines We do not know whether Novgos could affect your ability to drive a car or operate machines. HOW TO USE Novgos The implant is given as an injection under the skin on your stomach by your doctor. Novgos should be given every month (four weeks). Always remind your doctor or nurse to set up an appointment for your next injection.

This dosage is the same for patients with impaired kidney or liver function and for elderly patients. If you think that the symptoms have changed or worsened, please ask your doctor. He will be able to decide if any changes are needed to your treatment. If you use more Novgos than you should If you receive an injection too early (less than four weeks after the previous injection) please inform your doctor. If you forget to use Novgos Please talk to your doctor if you think the 4-weekly use of Novgos has been forgotten. If you stop using Novgos Generally the treatment with Novgos is a long-term treatment. It is important that you keep on receiving your treatment, even if you are feeling well, unless your doctor decides that it is time to stop the treatment.

If you have further questions regarding the use of this medicine, please ask your doctor or pharmacist. POSSIBLE SIDE EFFECTS Like all medicines, Novgos can cause side effects, although not everybody gets them. • Spravato (esketamine) is a rapid acting, nasal spray formulation of a non-competitive N-methyl D-aspartate. • Jeuveau (prabotulinumtoxinA) is a botulinum toxin type A formulation for the temporary improvement in the. • Ultomiris (ravulizumab-cwvz) is a long-acting C5 complement inhibitor for the treatment of paroxysmal. • Motegrity (prucalopride) is a selective serotonin type 4 (5‑HT4) receptor agonist for the treatment of c. • Xospata (gilteritinib) is a kinase inhibitor indicated for the treatment of patients who have relapsed.

• Daurismo (glasdegib) is a hedgehog pathway inhibitor indicated for the combination treatment of adult.